Rabbit Monoclonal Antibody to XIAP
货号:
P22180
别名:
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
应用:
WB
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q60989
规格:
目录价
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Description |
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Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. |
Specification |
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Aliases | API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3 |
Entrez GeneID | 11798 |
Swissprot | Q60989 |
WB Predicted band size | Calculated MW: 56 kDa; Observed MW: 53 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of mouse XIAP |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |