Rabbit Monoclonal Antibody to Wnt5a
货号：
P22178
别名：
WNT5A; Protein Wnt-5a
应用：
WB,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P41221
规格：
目录价
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Description |
|---|
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. |
Specification |
|
|---|---|
| Aliases | WNT5A; Protein Wnt-5a |
| Entrez GeneID | 7474 |
| Swissprot | P41221 |
| WB Predicted band size | Calculated MW: 42 kDa; Observed MW: 45 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human Wnt5a |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IF | 1/50-1/200 |
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