Rabbit Monoclonal Antibody to RYK
货号：
P22204
别名：
ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik
应用：
WB,IP,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P34925
规格：
目录价
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Description |
|---|
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. |
Specification |
|
|---|---|
| Aliases | ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik |
| Entrez GeneID | 6259 |
| Swissprot | P34925 |
| WB Predicted band size | Calculated MW: 68 kDa; Observed MW: 72 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human RYK |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of RYK in Hela, A549, HL-60, U2OS, U87-MG lysates using RYK antibody.
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Immunocytochemistry analysis of RYK (green) in hela using RYK antibody,and DAPI(blue)
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using RYK antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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