Rabbit Monoclonal Antibody to MGMT
货号:
P22456
别名:
Methylated-DNA--protein-cysteine methyltransferase
应用:
WB,IP
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P16455
规格:
目录价
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Description |
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MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. |
Specification |
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Aliases | Methylated-DNA--protein-cysteine methyltransferase |
Entrez GeneID | 4255 |
Swissprot | P16455 |
WB Predicted band size | Calculated MW: 22 kDa; Observed MW: 22 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic peptide of human MGMT |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IP | 1/10-1/20 |