Rabbit Monoclonal Antibody to RAP80
货号：
P22554
别名：
RAP80; X2HRIP110
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96RL1
规格：
目录价
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Description |
|---|
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). |
Specification |
|
|---|---|
| Aliases | RAP80; X2HRIP110 |
| Entrez GeneID | 51720 |
| Swissprot | Q96RL1 |
| WB Predicted band size | Calculated MW: 80 kDa; Observed MW: 80 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human RAP80 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of RAP80 in Hela, A549, HL-60, U2OS lysates using RAP80 antibody.
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Immunocytochemistry analysis of RAP80 (green) in Hela using RAP80 antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using RAP80 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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