Rabbit Monoclonal Antibody to Superoxide Dismutase 1
货号：
P22590
别名：
SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
应用：
WB,IHC,IF
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P00441
规格：
目录价
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Description |
|---|
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions. |
Specification |
|
|---|---|
| Aliases | SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1 |
| Entrez GeneID | 6647 |
| Swissprot | P00441 |
| WB Predicted band size | Calculated MW: 16 kDa; Observed MW: 16 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic peptide of human Superoxide Dismutase 1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of Superoxide Dismutase 1 in A549, HL-60, C6 lysates using Superoxide Dismutase 1 antibody.
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Immunocytochemistry analysis of Superoxide Dismutase 1 (green) in HCT116 using Superoxide Dismutase 1 antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using Superoxide Dismutase 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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