Rabbit Monoclonal Antibody to Insulin Degrading Enzyme
货号：
P22646
别名：
INSULYSIN; Insulin degrading enzyme; IDE
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P14735
规格：
目录价
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Description |
|---|
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. |
Specification |
|
|---|---|
| Aliases | INSULYSIN; Insulin degrading enzyme; IDE |
| Entrez GeneID | 3416 |
| Swissprot | P14735 |
| WB Predicted band size | Calculated MW: 118 kDa; Observed MW: 118 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human IDE |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of Insulin Degrading Enzyme/IDE in Hela, A549, HL-60, U2OS lysates using Insulin Degrading Enzyme antibody.
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Insulin Degrading Enzyme/IDE antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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