Rabbit Monoclonal Antibody to HMGB1
货号:
P22677
别名:
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P09429
规格:
目录价
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Description |
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High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription. |
Specification |
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Aliases | HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1 |
Entrez GeneID | 3146 |
Swissprot | P09429 |
WB Predicted band size | Calculated MW: 25 kDa; Observed MW: 25 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic peptide of human HMGB1 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |