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Rabbit Monoclonal Antibody to HMGB1
货号: P22677
别名: HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P09429
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Description

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.

Specification

Aliases HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Entrez GeneID 3146
Swissprot P09429
WB Predicted band size Calculated MW: 25 kDa; Observed MW: 25 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human HMGB1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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