Rabbit Monoclonal Antibody to JAK2
货号：
P22711
别名：
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
O60674
规格：
目录价
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Description |
|---|
Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
Specification |
|
|---|---|
| Aliases | JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2 |
| Entrez GeneID | 3717 |
| Swissprot | O60674 |
| WB Predicted band size | Calculated MW: 131 kDa; Observed MW: 131 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthetic peptide of human JAK2 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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