Rabbit Polyclonal Antibody to Thrombomodulin
货号:
P22769
别名:
CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
应用:
WB,IP,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P07204
规格:
目录价
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Description |
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Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice. |
Specification |
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Aliases | CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM |
Entrez GeneID | 7056 |
Swissprot | P07204 |
WB Predicted band size | Calculated MW: 60 kDa; Observed MW: 60 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human Thrombomodulin |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |