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Rabbit Polyclonal Antibody to Thrombomodulin
货号: P22769
别名: CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
应用: WB,IP,IHC,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: P07204
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Description

Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

Specification

Aliases CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
Entrez GeneID 7056
Swissprot P07204
WB Predicted band size Calculated MW: 60 kDa; Observed MW: 60 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Thrombomodulin
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200
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