Rabbit Polyclonal Antibody to IRF1
货号：
P22793
别名：
IRF1; Interferon regulatory factor 1; IRF-1
应用：
WB,IP,IHC,IF,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P10914
规格：
目录价
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Description |
|---|
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body. |
Specification |
|
|---|---|
| Aliases | IRF1; Interferon regulatory factor 1; IRF-1 |
| Entrez GeneID | 3659 |
| Swissprot | P10914 |
| WB Predicted band size | Calculated MW: 37 kDa; Observed MW: 48 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human IRF1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| FCM | 1/50-1/100 |
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