Rabbit Polyclonal Antibody to DGCR8
货号：
P22802
别名：
DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha
应用：
WB,IP,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q8WYQ5
规格：
目录价
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Description |
|---|
Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. |
Specification |
|
|---|---|
| Aliases | DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha |
| Entrez GeneID | 54487 |
| Swissprot | Q8WYQ5 |
| WB Predicted band size | Calculated MW: 86 kDa; Observed MW: 100 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human DGCR8 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IF | 1/50-1/200 |
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