Rabbit Polyclonal Antibody to Cyclin E2
货号：
P22811
别名：
CCNE2; G1/S-specific cyclin-E2
应用：
WB,IP,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O96020
规格：
目录价
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Description |
|---|
The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. |
Specification |
|
|---|---|
| Aliases | CCNE2; G1/S-specific cyclin-E2 |
| Entrez GeneID | 9134 |
| Swissprot | O96020 |
| WB Predicted band size | Calculated MW: 47 kDa; Observed MW: 50 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Cyclin E2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
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