Rabbit Polyclonal Antibody to Chk2
货号：
P22821
别名：
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
应用：
WB,IP,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O96017
规格：
目录价
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Description |
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These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. |
Specification |
|
|---|---|
| Aliases | CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2 |
| Entrez GeneID | 11200 |
| Swissprot | O96017 |
| WB Predicted band size | Calculated MW: 61 kDa; Observed MW: 61 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Chk2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of Chk2 in (1) HeLa lysates; (2) 293T lysates using Chk2 antibody.
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Immunofluorescence analysis of Chk2 in Hela using Chk2 antibody.
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Immunohistochemistry analysis of paraffin-embedded Human testis using Chk2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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