Rabbit Polyclonal Antibody to FOXO4
货号:
P22863
别名:
FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1
应用:
WB,IP,IF,FCM
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P98177
规格:
目录价
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Description |
|---|
The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. |
Specification |
|
|---|---|
| Aliases | FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1 |
| Entrez GeneID | 4303 |
| Swissprot | P98177 |
| WB Predicted band size | Calculated MW: 54 kDa; Observed MW: 65 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human FoxO4 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IF | 1/50-1/200 |
| FCM | 1/50-1/100 |




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