Mouse Monoclonal Antibody to GH1
货号:
31084
别名:
GH; GHN; GH-N; GHB5; hGH-N; IGHD1B
应用:
FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P01242
规格:
目录价
在线咨询
Description |
---|
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. |
References |
---|
1.Asian Pac J Cancer Prev. 2015;16(13):5421-5. 2.Tumour Biol. 2014 May;35(5):4529-38. |
Specification |
|
---|---|
Aliases | GH; GHN; GH-N; GHB5; hGH-N; IGHD1B |
Entrez GeneID | 2688 |
Swissprot | P01242 |
clone | 3H1C2 |
WB Predicted band size | 24.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human GH1 (AA: 1-217) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |