Mouse Monoclonal Antibody to MIB1
货号：
31101
别名：
MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2
应用：
WB,FCM
反应种属：
Human,Monkey
抗体类型：
Primary antibody
Swissprot：
Q86YT6
规格：
目录价
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Description |
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This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). |
References |
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| 1.J Cell Sci. 2015 May 1;128(9):1674-82. 2.Cell Res. 2012 Mar;22(3):603-6. |
Specification |
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|---|---|
| Aliases | MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2 |
| Entrez GeneID | 57534 |
| Swissprot | Q86YT6 |
| clone | 2A7B1 |
| WB Predicted band size | 110kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Monkey |
| Immunogen | Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using MIB1 mouse mAb against Hela (1) and COS7 (2) cell lysate.
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Flow cytometric analysis of Hela cells using MIB1 mouse mAb (green) and negative control (red).
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