Rabbit Polyclonal Antibody to Axin 2
货号：
P22926
别名：
Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y2T1
规格：
目录价
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Description |
|---|
Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin. |
Specification |
|
|---|---|
| Aliases | Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin |
| Entrez GeneID | 8313 |
| Swissprot | Q9Y2T1 |
| WB Predicted band size | Calculated MW: 94 kDa; Observed MW: 94 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human Axin2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
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