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Rabbit Polyclonal Antibody to Menin
货号: P22962
别名: MEN1; SCG2; Menin
应用: WB,IP,IHC,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: O00255
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Description

Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

Specification

Aliases MEN1; SCG2; Menin
Entrez GeneID 4221
Swissprot O00255
WB Predicted band size Calculated MW: 68 kDa; Observed MW: 68 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Menin
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200
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