Rabbit Polyclonal Antibody to Menin
货号:
P22962
别名:
MEN1; SCG2; Menin
应用:
WB,IP,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O00255
规格:
目录价
在线咨询
Description |
---|
Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes. |
Specification |
|
---|---|
Aliases | MEN1; SCG2; Menin |
Entrez GeneID | 4221 |
Swissprot | O00255 |
WB Predicted band size | Calculated MW: 68 kDa; Observed MW: 68 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human Menin |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |