Rabbit Polyclonal Antibody to FADD
货号:
P23004
别名:
FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
应用:
WB,IHC,FCM
反应种属:
Mouse
抗体类型:
Primary antibody
Swissprot:
Q61160
规格:
目录价
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Description |
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Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
Specification |
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Aliases | FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1 |
Entrez GeneID | 14082 |
Swissprot | Q61160 |
WB Predicted band size | Calculated MW: 23 kDa; Observed MW: 28 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Mouse |
Immunogen | A synthesized peptide derived from mouse FADD |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
FCM | 1/50-1/100 |