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Rabbit Polyclonal Antibody to FADD
货号: P23004
别名: FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
应用: WB,IHC,FCM
反应种属: Mouse
抗体类型: Primary antibody
Swissprot: Q61160
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Description

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Specification

Aliases FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
Entrez GeneID 14082
Swissprot Q61160
WB Predicted band size Calculated MW: 23 kDa; Observed MW: 28 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen A synthesized peptide derived from mouse FADD
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
FCM 1/50-1/100
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