Mouse Monoclonal Antibody to Mouse TUG
货号:
20048
别名:
ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
应用:
WB
反应种属:
Mouse
抗体类型:
Primary antibody
Swissprot:
Q9BZE9
规格:
目录价
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Description |
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The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin. |
References |
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1. Nature 2003,425:727 - 733. |
Specification |
|
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Aliases | ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9 |
Entrez GeneID | 79058 |
Swissprot | Q9BZE9 |
clone | 4A11A6G11 |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Mouse |
Immunogen | Purified recombinant fragment of TUG expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |