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Mouse Monoclonal Antibody to Mouse TUG
货号: 20048
别名: ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
应用: WB
反应种属: Mouse
抗体类型: Primary antibody
Swissprot: Q9BZE9
规格:
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Description

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

References

1. Nature 2003,425:727 - 733.

Specification

Aliases ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
Entrez GeneID 79058
Swissprot Q9BZE9
clone 4A11A6G11
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen Purified recombinant fragment of TUG expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000
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