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Mouse Monoclonal Antibody to SYK
货号: 31103
别名: p72-Syk
应用: WB,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P43405
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Description

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References

1.Clin Cancer Res. 2015 Jun 1;21(11):2538-45.
2.PLoS One. 2014 Feb 11;9(2):e87610.

Specification

Aliases p72-Syk
Entrez GeneID 6850
Swissprot P43405
clone 3D1G10
WB Predicted band size 72kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human SYK (AA: 217-356) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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