Mouse Monoclonal Antibody to SYK
货号:
31102
别名:
p72-Syk
应用:
IF,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P43405
规格:
目录价
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Description |
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This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
References |
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1.Clin Cancer Res. 2015 Jun 1;21(11):2538-45. 2.PLoS One. 2014 Feb 11;9(2):e87610. |
Specification |
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Aliases | p72-Syk |
Entrez GeneID | 6850 |
Swissprot | P43405 |
clone | 2G11E6 |
WB Predicted band size | 72kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human SYK (AA: 217-356) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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IF | 1/50 - 1/250 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using SYK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using SYK mouse mAb (green) and negative control (red).