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Rabbit Polyclonal Antibody to Integrin beta 4
货号: P23097
别名: CD104
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: A2A863
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Description

Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Specification

Aliases CD104
Entrez GeneID 192897
Swissprot A2A863
WB Predicted band size Calculated MW: 202 kDa; Observed MW: 202 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Recombinant protein of mouse Integrin beta 4
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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