Rabbit Polyclonal Antibody to Hsp27
货号:
P23123
别名:
HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P04792
规格:
目录价
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Description |
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Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. |
Specification |
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Aliases | HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27 |
Entrez GeneID | 3315 |
Swissprot | P04792 |
WB Predicted band size | Calculated MW: 23 kDa; Observed MW: 27 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around aa. 80~84 (Q-L-S-S-G) derived from Human HSP27. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of Hsp27 in K562 and Hela lysates using HSP27 (Ab82) antibody.
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Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using HSP27 (Ab82) antibody(left) or the same antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.