Rabbit Polyclonal Antibody to TAK1
货号:
P23139
别名:
MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
应用:
WB,IHC,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
O43318
规格:
目录价
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Description |
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Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B. |
Specification |
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Aliases | MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1 |
Entrez GeneID | 6885 |
Swissprot | O43318 |
WB Predicted band size | Calculated MW: 67 kDa; Observed MW: 70 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |
ELISA | 1/10000 |
Product Image
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Western blot analysis of TAK1 in Jurkat lysates, treated with heat shock lysates using TAK1 antibody. The lane on the right is blocked with the synthesized peptide.
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Immunofluorescence analysis of TAK1 in rat kidney using Tak1 antibody(red),and DAPI (blue).
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Immunofluorescence analysis of TAK1 in mouse kidney using Tak1 antibody(red),and DAPI (blue).
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Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using TAK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.