Rabbit Polyclonal Antibody to HEXIM1
货号：
P23155
别名：
CLP1; EDG1; HIS1; MAQ1
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O94992
规格：
目录价
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Description |
|---|
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:14580347, PubMed:15713661, PubMed:15201869). In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:12832472, PubMed:14580347, PubMed:15713661, PubMed:15201869). May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity (PubMed:15940264, PubMed:15941832, PubMed:17088550). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). |
Specification |
|
|---|---|
| Aliases | CLP1; EDG1; HIS1; MAQ1 |
| Entrez GeneID | 10614 |
| Swissprot | O94992 |
| WB Predicted band size | Calculated MW: 41 kDa; Observed MW: 41 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HEXIM1. AA range:181-230 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis of HEXIM1 in rat HEART lysates using HEXIM1 antibody.
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Western blot analysis of HEXIM1 in NIH/3T3 lysates using HEXIM1 antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of HEXIM1 in theHeLa lysates using HEXIM1 antibody
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Immunofluorescence analysis of HEXIM1 in HeLa using HEXIM1 antibody. The picture on the right is blocked using the synthesized peptide.
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