Rabbit Polyclonal Antibody to CaMKII alpha/delta
货号：
P23146
别名：
CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UQM7/Q13557
规格：
目录价
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Description |
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The product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for CAMK2A. |
Specification |
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|---|---|
| Aliases | CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II |
| Entrez GeneID | 815/817 |
| Swissprot | Q9UQM7/Q13557 |
| WB Predicted band size | Calculated MW: 54 kDa; Observed MW: 54 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta. AA range:256-305 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis of CaMKII alpha/delta in NIH3T3/K562 lysates using CaMKII alpha/delta antibody.
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Western blot analysis of CaMKII alpha/delta in NIH/3T3 and K562 lysates using CaMKII alpha/delta antibody.The lane on the right is blocked with the synthesized peptide.
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Immunofluorescence analysis of CaMKII alpha/delta in MCF-7 using CaMK2 alpha/delta antibody. The picture on the right is blocked using the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded Human brain tissue using CaMK2 alpha/delta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.
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