产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Mouse Monoclonal Antibody to HLA-DRA
货号: 31113
别名: MLRW; HLA-DRA1
应用: WB,IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P01903
规格:
目录价
在线咨询

Description

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

References

1.Int J Immunogenet. 2014 Dec;41(6):508-11.
2.Am J Rhinol Allergy. 2012 Jan-Feb;26(1):12-7.

Specification

Aliases MLRW; HLA-DRA1
Entrez GeneID 3122
Swissprot P01903
clone 1C11A5
WB Predicted band size 28.6kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IF 1/100 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852