Rabbit Polyclonal Antibody to LexA DNA Binding Region
货号：
P23205
别名：
lexa dna binding region
应用：
WB
反应种属：
Cyanobacteria
抗体类型：
Primary antibody
Swissprot：
P0A7C2
规格：
目录价
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Description |
|---|
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment. |
Specification |
|
|---|---|
| Aliases | lexa dna binding region |
| Entrez GeneID | 948544 |
| Swissprot | P0A7C2 |
| WB Predicted band size | Refer to figures |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Cyanobacteria |
| Immunogen | Recombinant Protein of LexA DNA Binding Region |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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