Rabbit Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2 A/B
货号：
P23238
别名：
UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-con
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P49459/P63146
规格：
目录价
在线咨询
Description |
|---|
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. |
Specification |
|
|---|---|
| Aliases | UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B |
| Entrez GeneID | 7319/7320 |
| Swissprot | P49459/P63146 |
| WB Predicted band size | Calculated MW: 17 kDa; Observed MW: 17 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from the C-terminal region of human UBE2A/B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ELISA | 1/10000 |
Product Image
-
Western blot analysis of Ubiquitin Conjugating Enzyme E2 A/B in Jurkat lysates using UBE2A/B antibody.
-
Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Immunohistochemistry analysis of paraffin-embedded mouse brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
鄂公网安备42018502007531号
