Rabbit Polyclonal Antibody to EYA1/4
货号：
P23264
别名：
Eyes absent homolog 1; Eyes absent homolog 4
应用：
IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q99502/O95677
规格：
目录价
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Description |
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Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. |
Specification |
|
|---|---|
| Aliases | Eyes absent homolog 1; Eyes absent homolog 4 |
| Entrez GeneID | 2138/2070 |
| Swissprot | Q99502/O95677 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide from human protein at AA range: 271-320 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
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|---|---|
| IHC | 1/50-1/100 |
| ELISA | 1/10000 |
Product Image
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Immunohistochemical analysis of paraffin-embedded Human tonsils using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemistry analysis of paraffin-embedded Human brain using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemistry analysis of paraffin-embedded Human brain using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemistry analysis of paraffin-embedded Human kidney using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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