Mouse Monoclonal Antibody to CIRBP
货号：
31147
别名：
CIRP
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q14011
规格：
目录价
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Description |
|---|
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
References |
|---|
| 1.Med Sci Monit. 2015 May 2;21:1256-60. 2.Int J Gynecol Pathol. 2003 Jul;22(3):240-7. |
Specification |
|
|---|---|
| Aliases | CIRP |
| Entrez GeneID | 1153 |
| Swissprot | Q14011 |
| clone | 6E12B3 |
| WB Predicted band size | 18.6kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CIRBP (AA: 1-90) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CIRBP mouse mAb against SW480 (1), PC-3 (2), A431 (3), and U251 (4) cell lysate.
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Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CIRBP mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CIRBP mouse mAb with DAB staining.
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