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Rabbit Polyclonal Antibody to CD130
货号: P23435
别名: Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: P40189
规格:
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Description

The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.

Specification

Aliases Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130
Entrez GeneID 3572
Swissprot P40189
WB Predicted band size Calculated MW: 104 kDa; Observed MW: 130-140kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen A synthesized peptide derived from human CD130/gp130
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5% BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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