Rabbit Polyclonal Antibody to p21
货号:
P23482
别名:
CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21
应用:
WB,IP,IHC,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P38936
规格:
目录价
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Description |
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The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D. |
Specification |
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Aliases | CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21 |
Entrez GeneID | 1026 |
Swissprot | P38936 |
WB Predicted band size | Calculated MW: 18 kDa; Observed MW: 21 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic peptide of human p21 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IHC | 1/50-1/100 |
FCM | 1/50-1/100 |