Mouse Monoclonal Antibody to CDC37
货号:
31158
别名:
P50CDC37
应用:
WB,FCM
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q16543
规格:
目录价
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Description |
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The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. |
References |
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1.Liver Int. 2015 Apr;35(4):1403-15. 2.Oncogene. 2009 Jan 15;28(2):157-69. |
Specification |
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Aliases | P50CDC37 |
Entrez GeneID | 11140 |
Swissprot | Q16543 |
clone | 6B3B7 |
WB Predicted band size | 44.5kDa |
Host/Isotype | Mouse IgG2a |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of human CDC37 (AA: 241-378) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CDC37 mouse mAb against K562 (1), LNcap (2), A431 (3), HEK293 (4), and C2C12 (5) cell lysate.
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Flow cytometric analysis of K562 cells using CDC37 mouse mAb (green) and negative control (red).