Rabbit Polyclonal Antibody to LEF1
货号：
P23515
别名：
LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
应用：
WB,IP,IHC,IF,FCM
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UJU2
规格：
目录价
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Description |
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Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). |
Specification |
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|---|---|
| Aliases | LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha |
| Entrez GeneID | 51176 |
| Swissprot | Q9UJU2 |
| WB Predicted band size | Calculated MW: 44 kDa; Observed MW: 25-58 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic peptide of human LEF1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| FCM | 1/50-1/100 |
Product Image
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Western blot analysis of LEF1 in C6 lysates using LEF1 antibody.
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Western blot analysis of LEF1 in Jurkat lysates using LEF1 antibody
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Immunocytochemistry analysis of LEF1 (green) in Jurkat using LEF1 antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human tonsil using LEF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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