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Mouse Monoclonal Antibody to APBA2
货号: 31156
别名: X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q99767
规格:
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Description

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

References

1.Neuroreport. 2012 Feb 15;23(3):146-51.
2.Autism Res. 2009 Dec;2(6):359-64.

Specification

Aliases X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
Entrez GeneID 321
Swissprot Q99767
clone 7G5G11
WB Predicted band size 82.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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