Rabbit Polyclonal Antibody to Cyclin D1
货号：
P23614
别名：
CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1
应用：
WB,IP,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P24385
规格：
目录价
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Description |
|---|
Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. |
Specification |
|
|---|---|
| Aliases | CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1 |
| Entrez GeneID | 595 |
| Swissprot | P24385 |
| WB Predicted band size | Calculated MW: 34 kDa; Observed MW: 34 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human Cyclin D1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of Cyclin D1 in 3T3 lysates using Cyclin D1 antibody.
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Western blot analysis of Cyclin D1 in MCF-7, C6, PC-12 lysates using Cyclin D1 antibody.
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cyclin D1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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