Rabbit Polyclonal Antibody to SENP2
货号：
P30004
别名：
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9HC62
规格：
目录价
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Description |
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SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. |
Specification |
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|---|---|
| Aliases | Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331 |
| Entrez GeneID | 59343 |
| Swissprot | Q9HC62 |
| WB Predicted band size | 67.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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The SENP2 C-term polyclonal antibody (Cat. #P30004) is used in Western blot to detect SENP2 in mouse heart tissue lysate.
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Western blot analysis of anti-SENP2 Antibody (C-term)(Cat. #P30004) in HL60 cell line lysates (35ug/lane). SENP2(arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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