Rabbit Polyclonal Antibody to Mouse Dnmt3L
货号：
P30027
别名：
DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
应用：
WB
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9CWR8
规格：
目录价
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Description |
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mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger. |
Specification |
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|---|---|
| Aliases | DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l |
| Entrez GeneID | 54427 |
| Swissprot | Q9CWR8 |
| WB Predicted band size | 48.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
Product Image
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Western blot analysis of Mouse Dnmt3L Antibody (Cat. #P30027) in Hela cell line lysates (35ug/lane). Dnmt3l (arrow) was detected using the purified Pab.
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Dnmt3l Antibody (C403) (Cat. #P30027) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dnmt3l antibody detected the Dnmt3l protein (arrow).
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