Rabbit Polyclonal Antibody to LOK (C-term E707)
货号：
P30042
别名：
Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, STK10, LOK
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O94804
规格：
目录价
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Description |
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This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. |
Specification |
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|---|---|
| Aliases | Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, STK10, LOK |
| Entrez GeneID | 6793 |
| Swissprot | O94804 |
| WB Predicted band size | 112.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This LOK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human LOK. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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The anti-LOK Pab (Cat. #P30042) is used in Western blot to detect LOK in Jurkat cell lysate.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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