Rabbit Polyclonal Antibody to Phospho-mouse FADD(S191)
货号：
P30124
别名：
FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q61160
规格：
目录价
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Description |
|---|
FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
Specification |
|
|---|---|
| Aliases | FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1 |
| Entrez GeneID | 14082 |
| Swissprot | Q61160 |
| WB Predicted band size | 23.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD. |
| Formulation | Purified antibody in TBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
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