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Mouse Monoclonal Antibody to ARFGAP1
货号: 31185
别名: ARF1GAP; HRIHFB2281
应用: WB,FCM
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q8N6T3
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Description

The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

References

1.PLoS One. 2014 Nov 14;9(11):e111309.
2.Methods Enzymol. 2001;329:307-16.

Specification

Aliases ARF1GAP; HRIHFB2281
Entrez GeneID 55738
Swissprot Q8N6T3
clone 1C4E2
WB Predicted band size 44.7kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human ARFGAP1 (AA: 270-414) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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