Rabbit Polyclonal Antibody to UVRAG (C-term L555)
货号:
P30203
别名:
UV radiation resistance-associated gene protein, p63, UVRAG
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9P2Y5
规格:
目录价
在线咨询
Description |
---|
UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving the UVAG gene are associated with left-right axis malformation and mutations in the gene have been associated with colon cancer. |
Specification |
|
---|---|
Aliases | UV radiation resistance-associated gene protein, p63, UVRAG |
Entrez GeneID | 7405 |
Swissprot | Q9P2Y5 |
WB Predicted band size | 78.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human UVRAG. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
---|---|
WB | 1/1000 |