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Rabbit Polyclonal Antibody to UVRAG (C-term L555)
货号: P30203
别名: UV radiation resistance-associated gene protein, p63, UVRAG
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9P2Y5
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Description

UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving the UVAG gene are associated with left-right axis malformation and mutations in the gene have been associated with colon cancer.

Specification

Aliases UV radiation resistance-associated gene protein, p63, UVRAG
Entrez GeneID 7405
Swissprot Q9P2Y5
WB Predicted band size 78.2kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human UVRAG.
Formulation Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) .

Application

WB 1/1000
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