Mouse Monoclonal Antibody to PINK1
货号:
P30246
别名:
Serine/threonine-protein kinase PINK1, mitochondrial, BRPK, PTEN-induced putative kinase protein 1, PINK1
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
Q9BXM7
规格:
目录价
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Description |
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This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. |
Specification |
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Aliases | Serine/threonine-protein kinase PINK1, mitochondrial, BRPK, PTEN-induced putative kinase protein 1, PINK1 |
Entrez GeneID | 65018 |
Swissprot | Q9BXM7 |
WB Predicted band size | 62.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Recombinant PINK1 protein was used to produced this monoclonal antibody. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/100-1/500 |
Product Image
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Western blot analysis of anti-PINK1 Monoclonal Antibody (P30246) in mouse brain tissue lysates. PINK1(arrow) was detected using the ascites Mab. (dilution 1:500)
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Western blot analysis of PINK (arrow) using mouse monoclonal PINK antibody(Ascites). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the PINK gene (Lane 2) (Origene Technologies) (1:2000)
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Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PINK1 Monoclonal Antibody (Cat.#P30246), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Formalin-fixed and paraffin-embedded human Brain Cortex tissue reacted with PINK1 Monoclonal Antibody (Cat.#P30246), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.