Rabbit Polyclonal Antibody to S adenosylhomocysteine hydrolase (ACHY)
货号：
P30268
别名：
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, AHCY, SAHH
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P23526
规格：
目录价
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Description |
|---|
S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. |
Specification |
|
|---|---|
| Aliases | Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, AHCY, SAHH |
| Entrez GeneID | 191 |
| Swissprot | P23526 |
| WB Predicted band size | 47.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This S adenosylhomocysteine hydrolase (ACHY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-432 amino acids from the C-terminal region of human S adenosylhomocysteine hydrolase (ACHY). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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Western blot analysis of anti-AHCY Antibody (C-term)(Cat.#P30268) in HepG2 cell line lysates (35ug/lane). AHCY(arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AHCY antibody (C-term) (Cat.#P30268), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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