Rabbit Polyclonal Antibody to EXOSC8
货号：
P30338
别名：
Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9, EXOSC8, OIP2, RRP43
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96B26
规格：
目录价
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Description |
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EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity. |
Specification |
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|---|---|
| Aliases | Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9, EXOSC8, OIP2, RRP43 |
| Entrez GeneID | 11340 |
| Swissprot | Q96B26 |
| WB Predicted band size | 30.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
| FCM | 1/10-1/50 |
Product Image
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Western blot analysis of anti-EXOSC8 Antibody (C-term) (Cat.#P30338) in HL60 cell line lysates (35ug/lane). EXOSC8(arrow) was detected using the purified Pab.
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EXOSC8 Antibody (C-term) (Cat. #P30338) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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