Rabbit Polyclonal Antibody to IGFBP6
货号：
P30412
别名：
Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6, IBP6
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P24592
规格：
目录价
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Description |
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IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. |
Specification |
|
|---|---|
| Aliases | Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6, IBP6 |
| Entrez GeneID | 3489 |
| Swissprot | P24592 |
| WB Predicted band size | 25.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This IGFBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-200 amino acids from the C-terminal region of human IGFBP6. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
| FCM | 1/10-1/50 |
Product Image
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Western blot analysis of IGFBP6 Antibody (C-term) (Cat. #P30412) in CEM cell line lysates (35ug/lane). IGFBP6 (arrow) was detected using the purified Pab.
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Flow cytometric analysis of widr cells using IGFBP6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Formalin-fixed and paraffin-embedded human colon carcinoma reacted with IGFBP6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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