Mouse Monoclonal Antibody to Foxp3
货号：
20045
别名：
JM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3
应用：
IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9BZS1
规格：
目录价
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Description |
|---|
The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
References |
|---|
| 1. Roncador G et al. Eur J Immunol. 2005. 35:1681-1691. 2. Yisong YW. PNAS. 2005 102 (14): 5126-5131. |
Specification |
|
|---|---|
| Aliases | JM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3 |
| Entrez GeneID | 50943 |
| Swissprot | Q9BZS1 |
| clone | 2A11G9 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human Foxp3 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Confocal Immunofluorescence analysis of PANC-1 cells using FOXP3 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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Immunohistochemical analysis of paraffin-embedded human lymphocyto tissue, showing cytoplasmic and nuclear localization using Foxp3 mouse mAb with DAB staining.
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